Size and size range of particles are very important in. Gate graduate aptitude test in engineering pharmaceutical. Brummer rheology essentials of cosmetics springer isbn. The ft4 powder rheometer a universal powder tester for measuring powder flow properties and powder behavior. A material that is not cohesive and flows well, spreads out, forming a low. Powder characterization uniaxial powder testing for.
Studies on the micromeritic properties of ibuprofen microcapsules. Rheology and dma can help to investigate the optimum capsule process conditions and also evaluate the capsule properties with a controlled temperature and humidity. Our technology portfolio includes pycnometry, adsorption, dynamic chemisorption, particle size and shape, intrusion porosimetry, powder rheology, and activity testing of catalysts. Data and its importance in pharmaceutical roller compaction operations pdf. The unit of particle size most frequently used in micromeritics is micrometer, also called as a micron. Micromeritics is the science and technology of small particles. Sometimes the term is used for annular shear cells, but recently other methods using modern airbearing rheometers have been developed. Physical pharmacymicromeritics and powder rheology. Effective solutions for material characterization micromeritics instrument corporation is the worlds leading supplier of. Implication and evaluation of micromeritics in formulation 2. Methods for determining particle sizeoptical microscopy, sieving, sedimentation, particle volume measurement, particle shape and surface area, methods for determining surface area adsorption methods, air permeability methods, derived. Micromeritics instrument corporation hiring compliance. Micromeritics and powder rheology 1 micromeritics physical pharmacy unit i by abhijit debnath, asst.
Pdf micromeritics in pharmaceutical product development. Ppt micromeritics and powder rheology powerpoint presentation. Oct 07, 2018 micromeritics and powder rheology pdf download the term micromeritics was given to the science and technology of small particles by j. Oct 01, 2020 all rheology tests were done in triplicate after conditioning the powder using the instrument manufacturers suggested methodology. Functionality is covered in terms of capabilitie, requirement, implementation, and best practices. Nov 10, 2020 furthermore, those who are looking for suggestions for further possible uses of physisorption, chemisorption, mercury porosimetry, particle size characterization and powder rheology as well as microreaction technology should attend this webinar. Powder flow powder rheology is used to measure the dynamic flow and shear properties of powders as well as quantifying bulk properties such as density, compressibility and permeability. Procedure for preparation and reconstitution of pfizers covid19 vaccine step 1. Graduate pharmacy admission test which is commonly known as gpat is conducted by the officials of nta annually. Knowledge and control of the size and the size range of particles are of significant importance in pharmacy because the size and surface area of a particle related to the physical, chemical and pharmacologic properties of a drug. Micromeritics and powder rheology abhijit debnath april 19th, 2019 physical pharmacy 3rd yr unit 1 micromeritics and powder rheology theory and practice of physical pharmacy by gaurav jain martin s physical pharmacy and pharmaceutical sciences powered by create your own unique website with customizable templates. The ft4 was designed with one purpose in mind to characterize the rheology, or flow properties, of powders.
The splitting device, provided with the instrument, is intended to provide a fixed volume and mass of powder. Particle size and distribution, average particle size number and weight distribution, particle number, method of determining particle size and volume, optical microscopy, sieving, sedimentation, determining surface areas, permeability, adsorption, derived properties of powders, porosity. Jan 23, 2018 micromeritics and powder rheology pdf. Powder rheology is used to measure the dynamic flow and shear properties of powders as well as quantifying bulk properties such as density, compressibility. Ramayanas storyline and differences many ramayana books are published, however. Micromeritics in pharmaceutical product development.
It was determined that powder rheology, using the ft4 powder rheometer. In order to crack the gpat 2020 exam, one must completely go through the gpat syllabus 2020 pdf. Gpat syllabus 2020 pdf download gpat nta subjectwise. Study of flow properties of liquids is important for pharmacist working in the manufacture of several dosage forms, viz. It is the science and technology of small particles. Surface area and porosity are physical properties that impact the quality and character of solid phase materials. On attrition milling, the specific surface area of the powder increased to 3. Micromeretics and powder rheology reynolds number laminar. Dec 09, 2019 please use one of the following formats to cite this article in your essay, paper or report. Data can be saved, printed, or exported electronically in spreadsheet or pdf. Size and surface area of particles are related to physical, chemical and physiological properties of a drug. Micromeritics pdf micromeritics offers a large selection of gas sorption analyzers that will fulfill demanding requirements for determining surface area and porosity.
Methods for determining particle sizeoptical microscopy, sieving, sedimentation, particle volume measurement, particle shape and surface area, methods for determining surface area adsorption methods, air permeability methods, derived properties. Good flow properties of granules and powders are important in the. Materials with identical physical dimensions may exhibit entirely different performance profiles based on variations in the physical surface area of the two materials. Rheology is defined as the science of flow and deformation of. Each 5 ml of the 250mg reconstituted suspension contains 0. Micromeritics and powder rheology pdf a powder sample is characterized by three things. Powders with different particle sizes have different flow. Interfacial wall friction within the particles in a. Particle size and distribution, average particle size, number and weight distribution, particle number, methods for determining particle size by different methods, counting and separation method, particle shape, specific surface, methods for determining surface are, permeability, adsorption, derived properties micromeritics, physical pharmaceutics b. Rheological characterization of pharmaceutical powders. Micromeritics and rheology lab micromeritics by mrs regina a. Micromeritics is the worlds leading supplier of highperformance systems to characterize particles, powders and porous materials with a focus on physical properties, chemical activity, and flow properties. Access detailed explanations illustrated with images and videos to 120 questions.
The ft4 powder rheometer was originally designed to characterise the rheology, or flow properties, of powders. Measurement of flow property a introduction the flow properties of powder plays an important role in dosage form manufacturing process. Micromeritics and rheology lab micromeritics by mrs. Physical pharmacy 3rd yr unit 1 micromeritics and powder rheology a free powerpoint ppt presentation displayed as a flash slide. Building robust pharma physical properties analysis. Phd nibha institute of pharmaceutical sciences topics. Knowing the gpat 2020 syllabus will help candidates to be aware of topics through which the questions are being derived and asked in the examination.
Each 5 ml of reconstituted suspension contains 200 mg, 250 mg, or 400 mg amoxicillin as the trihydrate. Micromeritics instrument corporation company profile. During his time with the company, jamie has worked as a mentor with several academic groups and is an active member of astm f42. Micromeritics in physical pharmacy pdf meta search engine. Assessing the robustness of powder rheology and permeability. Physical pharmacy 3rd yr unit 1 micromeritics and powder rheology.
Sep 07, 2015 definition of rheology rheology is the sciencephysics that concerns with the flow of liquids and the deformation of solids. Sep 07, 2015 micromeritics micromeritics is the science and technology of small particles. Procedure for preparation and reconstitution of pfizers. Developing generic dry powder inhaler formulations using. Nov 09, 2020 pdf on jan 1, 2018, rahul maheshwari and others published micromeritics in pharmaceutical product development find, read and cite all the research you need on researchgate. Physical pharmacy micromeritics and powder rheology gate graduate aptitude test in engineering pharmaceutical engineering. Dec 03, 2018 micromeritics and powder rheology pdf micromeritics and powder rheology pdf the term micromeritics was given to the science and technology of small particles by j. Using rheology to characterize flow and viscoelastic. This remains a primary function today, but the instrument, accessories and methodologies have been continuously developed to the point where the ft4 is now considered. Micromeritics instruments corporation is a global provider of solutions for material characterization with bestinclass instrumentation and application expertise in five core areas. Micromeritics instrument corporation is the worlds leading supplier of highperformance systems to characterize particles, powders, and porous materials with a focus on physical properties, chemical activity, and flow properties. Download as ppt, pdf, txt or read online from scribd.
Micromeritics and powder rheology science info world. Micromeritics instruments corporation is a global provider of solutions for material characterization with bestinclass instrumentation and application expertise in these core areas. Candidates who are planning to appear for gpat 2020 exam must be aware of gpat syllabus. And nano ceramic powder dispersions can be prepared by using fructose for the. Micromeritics subsieve autosizer ii 5800 micromeritics. Physical pharmacymicromeritics and powder rheology gate. The successful formulation of suspensionsemulsions micromeritics and powder rheology tablets.
Micromeritics and powder rheology by abhijit debnath issuu. Professor faculty of pharmaceutical sciences pdm university 2. Temperature and humidity 100 200 300 400 loss modulus mpa 0 20 40 60 80 100 relative humidity % 0 2000. However, the flow properties of the powder are very essential to be determined as it depends on the particle size and shape and governs flow rate, thereby being a decisive factor in dosage and content uniformity moravkar et al. An introduction to industrial powder characterization. This technical report details fabricpool best practices for netapp ontap. Measuring and understanding the flow properties of powders.
Powder rheology flowability characteristics of powdered or granular materials a multivariate approach to powder flow measurements can precisely conclude that a combination of smaller roll gap and higher compaction force is more likely to result in more uniformconsistent granules which form a more efficiently packed powder bed typically. Each 5 ml of the 200mg reconstituted suspension contains 0. Powder characterization inline measurement of powder. Micromeritics and powder rheology pdf rarely found in pharmaceutical powders. Micromeritics instrument corporation 4,041 followers on linkedin. Physical pharmacy micromeritics and powder rheology. Introduction the science and technology of small particles was given by the name micromeritics by dalla valle micromeritics is the science and technology of small particles. Nov 03, 2020 from micromeritics instrument corporation nov 3 2020. Porosity voids defined as the ratio of the void volume to the bulk volume of the packing.
Powder flow characteristics are commonl y investigated by various measurements, such as handling angles, tap tes ting, she int j pharm. Outline of the talkdefinition and applications of micromeritics in pharmacy, fundamental properties of particles particle sizesize distribution and measurements. Jamie is also a regular contributor to conferences and workshops on the topic of powder rheology and works closely with clients on the application of the companys technology. Compliance engineer job in norcross, ga at micromeritics. Powder rheology is the study of the properties and characteristics of powders and granular media with advanced test methods similar to those in rheology where flow in liquids and soft matter are studied. Importance of micromeritics in pharmacy size and size range of particles are very important in pharmacy. Large scale manufacturing aspects unit operations and equipment used. Freeman technology and micromeritics to host material. The knowledge and control of the size of particles is. Thaw thaw vials of pfizerbiontech covid19 vaccine before use either by. Get to the point gate graduate aptitude test in engineering pharmaceutical engineering questions for your exams. Micromeritics is the science and technology of small particles and includes the study of the fundamental and derived properties of individual as. The asap is the amd platform for physisorption, gas porosimetry, surface area measurements and with accessories a range of other tests micromeritics in ireland for micromeritics and powder rheology pdf bet surface area, density, porosimetry midromeritics particulate systems.
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